pep-OVA-20mg-us
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pep-TPT-10mg-us
CAS 52232-67-4
Teriparatide is a synthetic 34-amino-acid fragment of human parathyroid hormone, PTH(1-34), retaining activity at the PTH1 receptor and studied for its effects on osteoblast lineage cells in bone-biology research models. Jilka et al., 1999 (PMID 10449436) documented increased mature osteoblast lifespan under intermittent exposure in mouse and human cell models. For Research Use Only. Not for human consumption. (58 words)
For laboratory research use only · Not for human or veterinary use.
Description
Teriparatide corresponds to the biologically active N-terminal 34 residues of the 84-amino-acid parathyroid hormone molecule, retaining activity at the PTH1 receptor. The way a short recorded message can carry the same instruction as a much longer one, this fragment reproduces the receptor-binding activity of the full-length hormone in a shorter, synthesizable sequence. Intermittent versus continuous exposure patterns are associated in the literature with divergent effects on bone cell populations — a distinction that has made PTH(1-34) a recurring subject in skeletal cell-biology research.
Jilka et al., 1999 (J Clin Invest, PMID 10449436) investigated intermittent parathyroid hormone exposure in mice, documenting an increase in mature osteoblast lifespan linked to suppression of osteoblast apoptosis, in both rodent and human cell culture models. Liu, Liu & Rosen, 2024 (Cells, PMID 38474370) reviewed PTH's dual role on mesenchymal cells within the bone marrow niche, examining how intermittent versus continuous exposure patterns are documented to diverge in their cellular pathway activation. Chen et al., 2021 (Biochem Pharmacol, PMID 34224692) reviewed PTH(1-34) signaling through the PTH1 receptor across osteoblastic lineage cells, osteocytes, and T cells in bone metabolism research.
For Research Use Only. Not for human consumption.
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Shipping & Storage
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In-transit handling
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Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
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