OVAGE
RUO
20mg
pep-OVA-20mg-us
Ovagen
$75.34Out of stock
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RUO
30mg
pep-SMX-30mg-us
Semax 30mg
CAS 80714-61-0
Semax is a synthetic heptapeptide fragment of ACTH(4-7), stabilized with a Pro-Gly-Pro sequence against enzymatic degradation. Stavchanskii et al. (Mol Biol (Mosk), 2011) investigated its effect on neurotrophin gene expression in rat brain tissue following carotid artery occlusion (PMID 22295573). For Research Use Only. Not for human consumption.
$101.19Out of stock
1
For laboratory research use only · Not for human or veterinary use.
Description
About this peptide
About This Compound
Semax (ACTH(4-7)-Pro-Gly-Pro) is a laboratory-synthesized heptapeptide derived from a fragment of adrenocorticotropic hormone, extended with a proline-glycine-proline sequence that increases its stability against enzymatic breakdown. The way a locksmith copies only the notches of a key that turn the lock, Semax reproduces a narrow structural segment of ACTH associated with central-nervous-system signaling pathways, without replicating the full hormone. It is studied in rodent models for its interaction with neurotrophin gene expression and stress-signaling systems.
Research Context
Stavchanskii et al. (Mol Biol (Mosk), 2011) examined Semax and its C-terminal Pro-Gly-Pro fragment for changes in neurotrophin and neurotrophin-receptor mRNA expression in rat brain tissue following carotid artery occlusion (PMID 22295573). Filippenkov et al. (Genes, 2023) used RNA-sequencing to characterize differentially expressed immune- and neurosignaling-related genes in rat frontal cortex following transient middle cerebral artery occlusion, comparing Semax with a related ACTH-derived peptide (PMID 37510287). Inozemtseva et al. (Eur J Pharmacol, 2024) studied Semax alongside a second ACTH(4-10) analog in a rodent chronic-stress paradigm, examining hippocampal BDNF levels and stress-associated behavioral markers (PMID 39442746).
Research Use Disclaimer
For Research Use Only. Not for human consumption.
Specifications
At a glance
- SKU
- pep-SMX-30mg-us
- Strength
- 30mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- COA
- Per lot, on file
- Availability
- Out of stock
Shipping & Storage
Handling this material
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
Common questions
No. Every SKU is labeled and sold strictly for laboratory research use only. These are not drugs, dietary supplements, or veterinary products. Research Use Only policy
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