OVAGE
RUO
20mg
pep-OVA-20mg-us
Ovagen
$75.34Out of stock
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RUO
10mg
pep-SMX-10+SEL-10-20mg-us
Semax + Selank 10mg (20mg total) 10mg
CAS 80714-61-0 · 129954-34-3
A paired preparation of two synthetic heptapeptides — Semax, an ACTH(4-10) analog, and Selank, a tuftsin analog — each studied in rodent models for activity on central nervous system signaling and gene expression. Sudarkina et al., 2021 (PMID 34201112) documented Semax's effect on brain protein expression after cerebral ischemia-reperfusion in rats. For Research Use Only. Not for human consumption. (59 words)
$64.89Out of stock
1
For laboratory research use only · Not for human or veterinary use.
Description
About this peptide
About This Compound
Semax is a synthetic heptapeptide analog of an N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10), lacking the hormonal activity of the parent molecule. Selank is a synthetic analog of tuftsin, an endogenous tetrapeptide, extended to a heptapeptide sequence. The way two instruments in the same section of an orchestra can be tuned to complementary registers, Semax and Selank are studied together in the literature for their overlapping activity on neurotrophin signaling and gene expression in the central nervous system, while each carries a distinct pharmacological research profile.
Research Context
Sudarkina et al., 2021 (Int J Mol Sci, PMID 34201112) investigated Semax in a rat model of cerebral ischemia-reperfusion, documenting changes in brain protein expression profiles linked to inflammation and cell-death pathways. Shadrina et al., 2010 (J Mol Neurosci, PMID 19662538) examined the temporal dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina following Semax administration. Stavchansky et al., 2022 (Genes, PMID 36553646) compared Semax against related glyproline peptides for effects on inflammatory and neurotransmitter gene clusters in the same ischemia-reperfusion model.
Konstantinopolsky et al., 2022 (Bull Exp Biol Med, PMID 36322304) studied Selank in a naloxone-precipitated morphine withdrawal model in rats, documenting changes in withdrawal-associated behavioral indices. Kolik et al., 2019 (Bull Exp Biol Med, PMID 31625062) investigated Selank's relationship to BDNF content in the hippocampus and prefrontal cortex of rats exposed to chronic ethanol. Kolomin et al., 2011 (Regul Pept, PMID 21609736) documented changes in inflammation-related gene expression in mouse spleen tissue following Selank exposure.
Research Use Disclaimer
For Research Use Only. Not for human consumption.
Specifications
At a glance
- SKU
- pep-SMX-10+SEL-10-20mg-us
- Strength
- 10mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- COA
- Per lot, on file
- Availability
- Out of stock
Shipping & Storage
Handling this material
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
Common questions
No. Every SKU is labeled and sold strictly for laboratory research use only. These are not drugs, dietary supplements, or veterinary products. Research Use Only policy
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