OVAGE
RUO
20mg
pep-OVA-20mg-us
Ovagen
$75.34Out of stock
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RUO
5mg
pep-PTD-5mg-us
PTD-DBM 5mg
PTD-DBM is a synthetic peptide fused to a Dishevelled-binding motif, investigated for its interference with the CXXC5–Dishevelled protein interaction within the Wnt/β-catenin signaling cascade in mouse tissue models. Lee et al., 2015 (J Exp Med, PMID 26056233) first characterized the peptide's activity in this pathway. For Research Use Only. Not for human consumption. (53 words)
$201.29Out of stock
1
For laboratory research use only · Not for human or veterinary use.
Description
About this peptide
About This Compound
PTD-DBM is a protein transduction domain fused to the Dishevelled-binding motif of CXXC5, a zinc-finger protein identified as a negative feedback regulator of Wnt/β-catenin signaling. The way a key can be cut to block a specific lock without touching any other lock in the building, PTD-DBM is designed to interrupt one specific protein-protein interaction — CXXC5 binding to Dishevelled — while leaving the rest of the signaling network untouched.
Research Context
Lee et al., 2015 (J Exp Med, PMID 26056233) first characterized PTD-DBM in a mouse model of cutaneous wound repair, documenting activation of β-catenin and collagen production when the CXXC5–Dishevelled interaction was disrupted. Ryu et al., 2023 (Cells, PMID 36831222) investigated PTD-DBM in a wound-induced hair neogenesis model, examining the CXXC5-mediated pathway alongside prostaglandin D2 signaling. Lee et al., 2023 (Advanced Healthcare Materials, PMID 36854308) studied PTD-DBM delivered via a hydrogel patch system in a mouse wound model, examining downstream markers of tissue regeneration.
Research Use Disclaimer
For Research Use Only. Not for human consumption.
Specifications
At a glance
- SKU
- pep-PTD-5mg-us
- Strength
- 5mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- COA
- Per lot, on file
- Availability
- Out of stock
Shipping & Storage
Handling this material
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
Common questions
No. Every SKU is labeled and sold strictly for laboratory research use only. These are not drugs, dietary supplements, or veterinary products. Research Use Only policy
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