Pinealon 20mg

About This Compound

Pinealon is a synthetic tripeptide, Glu-Asp-Arg, developed within the Khavinson short-peptide bioregulator research program. Structural biophysics work has examined how the Glu-Asp-Arg sequence interacts with DNA at the molecular level, while cell-culture studies have investigated the peptide's association with gene-expression changes. Much like a key that fits a narrow set of locks, the tripeptide's small size lets it interact with specific nucleotide sequences rather than broad cellular machinery.

Research Context

Silanteva et al. (2019), publishing in The Journal of Physical Chemistry B, used spectral, NMR, viscosimetry, and molecular dynamics methods to characterize how the Glu-Asp-Arg peptide interacts with the DNA double helix, documenting partial penetration into the major groove and an ion-dependent binding effect. Khavinson et al. (2014) investigated Glu-Asp-Arg and a related tripeptide in cultured aging brain cortex cells, documenting peptide-associated changes in serotonin-pathway gene expression identified through molecular docking analysis. Mendzheritsky et al. (2015) studied Pinealon alongside a related peptide preparation in aged-rat models of hypoxia and hypothermia, examining behavioral and neurochemical markers.

Research Use Disclaimer

For Research Use Only. Not for human consumption.