OVAGE
RUO
20mg
pep-OVA-20mg-us
Ovagen
$75.34Out of stock
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RUO
5mg
pep-OXB-5mg-us
Orexin B 5mg
Orexin-B is a hypothalamic neuropeptide derived from the same precursor as orexin-A, with distinct selectivity for the OX2 receptor subtype. Receptor-pharmacology studies have characterized ligand-dependent signaling differences between orexin-A and orexin-B at OX2 (Dale et al., 2026, Biochemical Pharmacology). For Research Use Only. Not for human consumption.
$67.09Out of stock
1
For laboratory research use only · Not for human or veterinary use.
Description
About this peptide
About This Compound
Orexin-B is the second of two neuropeptides generated by proteolytic processing of the prepro-orexin precursor. It shares partial sequence identity with orexin-A but shows distinct selectivity for the OX2 receptor subtype. Alongside orexin-A, it was identified as the endogenous ligand for a pair of previously orphan G protein-coupled receptors located in the lateral hypothalamus, and it continues to be used as a research tool for isolating OX2-specific signaling from the broader orexin system.
Research Context
Sakurai et al. (1998, Cell) identified orexin-B alongside orexin-A as products of the same precursor peptide and characterized their binding activity at two closely related G protein-coupled receptors. Dale et al. (2026, Biochemical Pharmacology) compared the intracellular signaling kinetics of OX2 receptor activation by orexin-A versus orexin-B using bioluminescence resonance energy transfer assays, reporting ligand-dependent differences in G-protein trafficking and beta-arrestin recruitment. Prischich et al. (2024, Cellular and Molecular Life Sciences) developed a photoswitchable analog of orexin-B for in vitro and in vivo receptor-pharmacology studies, demonstrating light-dependent control of OX2 receptor activity in zebrafish larvae.
Research Use Disclaimer
For Research Use Only. Not for human consumption.
Specifications
At a glance
- SKU
- pep-OXB-5mg-us
- Strength
- 5mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- COA
- Per lot, on file
- Availability
- Out of stock
Shipping & Storage
Handling this material
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
Common questions
No. Every SKU is labeled and sold strictly for laboratory research use only. These are not drugs, dietary supplements, or veterinary products. Research Use Only policy
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