OVAGE
RUO
20mg
pep-OVA-20mg-us
Ovagen
$75.34Out of stock
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RUO
10mg
pep-OXA-10mg-us
Orexin A 10mg
Orexin-A is a hypothalamic neuropeptide that activates the OX1 and OX2 G protein-coupled receptors alongside its paralog orexin-B. Central delivery of orexin-A to rats was documented to increase food consumption and track with fasting-induced changes in prepro-orexin expression (Sakurai et al., 1998, Cell). For Research Use Only. Not for human consumption.
$340.99Out of stock
1
For laboratory research use only · Not for human or veterinary use.
Description
About this peptide
About This Compound
Orexin-A is one of two neuropeptides, alongside orexin-B, derived from a common prepro-orexin precursor by proteolytic processing. It was first localized to neurons within the lateral and posterior hypothalamus and identified as the endogenous ligand for two closely related G protein-coupled receptors, OX1 and OX2, that had previously been classified as orphan receptors. The way a pilot light keeps a larger heating system primed and ready, orexin-A-expressing neurons are studied for their role in maintaining baseline arousal and metabolic signaling within the hypothalamic circuits they innervate.
Research Context
Sakurai et al. (1998, Cell) identified orexin-A and its receptors, reporting that central delivery of the peptide to rats was associated with increased food consumption and that prepro-orexin mRNA expression was upregulated during fasting in the animal model. Olsen, Furlong, and Carrive (2021, Behavioural Brain Research) examined microinjection of orexin-A into the central amygdala of rats, documenting changes in heart rate, arterial pressure, and general activity relative to vehicle controls. Pan et al. (2024, British Journal of Pharmacology) investigated orexin-A delivery in rodent and feline motion-sickness models (intracerebroventricular administration in rats; intranasal administration in cats), reporting behavioral effects linked to OX1 and OX2 receptor activity across several hypothalamic nuclei.
Research Use Disclaimer
For Research Use Only. Not for human consumption.
Specifications
At a glance
- SKU
- pep-OXA-10mg-us
- Strength
- 10mg
- Form
- Lyophilized powder
- Storage
- −20 °C, protected from light
- COA
- Per lot, on file
- Availability
- Out of stock
Shipping & Storage
Handling this material
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
Common questions
No. Every SKU is labeled and sold strictly for laboratory research use only. These are not drugs, dietary supplements, or veterinary products. Research Use Only policy
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