NA Semax Amidate 30mg

NA Semax Amidate is a modified analog of the synthetic heptapeptide Semax. Research on the parent peptide has examined its binding activity in rodent brain tissue (Dolotov et al., 2006, J Neurochem, PMID 16635254) and its relationship to BDNF and trkB expression (Dolotov et al., 2006, Brain Res, PMID 16996037). Sold research-grade only. For Research Use Only. Not for human consumption.

$102.29Out of stock

Manufactured in · 2 sources

NA Semax Amidate price table · by strength and origin
Strength	USA	China
30mg	$102.29Out of stockView	$92.99Out of stockView

For laboratory research use only · Not for human or veterinary use.

Description

About this peptide

About This Compound

NA Semax Amidate is a modified analog of Semax (Met-Glu-His-Phe-Pro-Gly-Pro), a synthetic heptapeptide derived from the 4-10 fragment of adrenocorticotropic hormone (ACTH). The N-acetyl and C-terminal amidate modifications are structural changes intended to alter peptide stability relative to the parent sequence. Research on the parent Semax peptide has focused on its binding activity in rodent brain tissue and its relationship to brain-derived neurotrophic factor (BDNF) signaling.

Research Context

Dolotov et al., 2006 identified specific, calcium-dependent binding sites for Semax in rat basal forebrain tissue and documented increased BDNF protein levels in that region following intranasal administration in a rodent model (J Neurochem, PMID 16635254). A related study by Dolotov et al., 2006 found that Semax administration increased BDNF and trkB expression in the rat hippocampus, alongside changes in conditioned avoidance behavior in the same animals (Brain Res, PMID 16996037). Shadrina et al., 2010 examined the time course of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina following Semax administration, observing region-specific and time-dependent expression patterns (J Mol Neurosci, PMID 19662538).