pep-OVA-20mg-us
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Biopunk supplies research-grade compounds for laboratory research. Our products are not for human or animal consumption and are not intended to diagnose, treat, cure, or prevent any disease.
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pep-CAG+SEM
CAG, a long-acting amylin analogue, has been studied alongside a second synthetic peptide sequence (internal designation Bio-1s) in early-phase clinical research. Enebo et al. (Lancet, 2021; PMID 33894838) examined pharmacokinetic and safety parameters when the two compounds were studied together in a phase 1b trial. For Research Use Only. Not for human consumption.
Strength · 3 variants
Manufactured in · 2 sources
| Strength | USA | China |
|---|---|---|
| 2.5mg | $73.69Out of stockView | $66.99Out of stockView |
| 10mg total | $123.19Out of stockView | $111.99Out of stockView |
| 20mg total | $98.99Out of stockView | $89.99Out of stockView |
For laboratory research use only · Not for human or veterinary use.
Description
CAG is a long-acting analogue of amylin, a pancreatic peptide hormone, chemically modified with a fatty-acid moiety for extended plasma exposure. It has been investigated alongside a second synthetic peptide sequence, referred to here by internal designation Bio-1s, across early-phase clinical research examining pharmacokinetics, tolerability, and safety when the two compounds are studied together. The way two instruments recorded on separate tracks can be studied individually and as a mix, CAG and Bio-1s have been evaluated both as standalone research subjects and as a co-administered pair in the cited literature.
Lau et al. (Lancet, 2021; PMID 34798060) conducted a multicentre, randomized, placebo-controlled and active-controlled phase 2 trial of CAG alone across ten countries, examining a range of CAG doses and measuring safety, tolerability, and pharmacodynamic endpoints in adult study participants. Enebo et al. (Lancet, 2021; PMID 33894838) conducted a phase 1b trial evaluating the concomitant administration of CAG with Bio-1s, measuring pharmacokinetic and pharmacodynamic parameters — including exposure, half-life, and clearance — of both compounds when studied together. Lau et al. (Journal of Medicinal Chemistry, 2015; PMID 26308095) documented the chemical design process for the Bio-1s peptide sequence, describing the fatty-acid conjugation strategy used to extend plasma half-life relative to earlier peptide analogues, characterized in mini-pig pharmacokinetic studies.
For Research Use Only. Not for human consumption.
Specifications
Lab reports
We independently test selected batches and publish those reports. Not every batch has one, and this strength and origin does not have a published report right now. You can read how certificates of analysis work, or browse every report we have published.
Shipping & Storage
Shipping
Orders ship within 24 hours. Delivered via USPS Priority or standard FedEx unless expedited shipping is selected at checkout. Tracking is emailed on dispatch and mirrored in your account.
In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Where a published Certificate of Analysis exists for your strength and origin, it is on the COA tab. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
Frequently asked
We independently test selected batches at a third-party lab and publish those certificates of analysis. Not every batch has one. The COA tab on each product shows whether the strength and origin you picked has a published report.
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