B12 10ml

About This Compound

B12 is a research-grade preparation of cyanocobalamin, a cobalt-containing corrinoid compound obtained through diet or microbial synthesis. In human biochemistry, cobalamin is documented in the literature as the precursor of two coenzyme forms — methylcobalamin and adenosylcobalamin — that participate in distinct enzymatic reactions. The way a key unlocks a specific lock, each coenzyme form is matched to one enzyme: methylcobalamin pairs with methionine synthase, adenosylcobalamin pairs with methylmalonyl-CoA mutase.

Research Context

Kräutler (Subcell Biochem, 2012; PMID 22116707) reviewed the biochemistry of B12-coenzyme forms in human metabolism, describing methylcobalamin as the cofactor for methionine synthase and adenosylcobalamin as the cofactor for methylmalonyl-CoA mutase. Fedosov (Subcell Biochem, 2012; PMID 22116708) documented the molecular transport pathway for cobalamin, characterizing the roles of haptocorrin, intrinsic factor, and transcobalamin in selective cobalamin assimilation. Lyon et al. (Nutrients, 2020; PMID 32961717) reviewed cobalamin's role, alongside folate, in one-carbon metabolism pathways that generate methyl groups for DNA synthesis, amino acid homeostasis, and epigenetic regulation research.

Research Use Disclaimer

For Research Use Only. Not for human consumption.