pep-OVA-20mg-us
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pep-ACT-5mg-us
CAS 9002-60-2
ACTH 1-39 is the full-length, 39-amino acid form of adrenocorticotropic hormone, a melanocortin peptide characterized in the literature as engaging melanocortin receptor 4 on glial and neuronal populations in addition to its classical adrenal receptor. Lisak et al. (Experimental Neurology, 2015; PMID 26300474) reported that ACTH 1-39 protected isolated rat forebrain neurons from apoptotic and excitotoxic insults in vitro. For Research Use Only. Not for human consumption.
For laboratory research use only · Not for human or veterinary use.
Description
ACTH 1-39 is the complete, biologically active form of adrenocorticotropic hormone, a 39-amino acid peptide member of the melanocortin family. It has been characterized in the literature as engaging melanocortin receptor subtypes across multiple tissue systems, including the adrenal cortex and the central nervous system. The way a single master key can open more than one type of lock, ACTH 1-39 is described in research as acting on melanocortin receptor 2 in adrenal tissue and melanocortin receptor 4 in glial and neuronal populations.
Lisak et al. (Journal of the Neurological Sciences, 2016; PMID 26944112) documented that ACTH 1-39 protected oligodendrocytes in mixed glial cultures from excitotoxic, oxidative, and inflammation-related injury, and found that conditioned medium from ACTH-treated astroglia carried a similar protective effect. Lisak et al. (Experimental Neurology, 2015; PMID 26300474) reported that ACTH 1-39 protected isolated rat forebrain neurons in vitro from apoptotic, excitotoxic, and inflammation-related insults across a panel of toxic agents. Phillips et al. (Journal of Physiology, 1996; PMID 8815218) investigated circulating ACTH(1-39) in the fetal sheep model, documenting its association with adrenal growth and steroidogenic enzyme expression following surgical disconnection of the hypothalamus and pituitary.
For Research Use Only. Not for human consumption.
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Shipping & Storage
Shipping
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In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
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