pep-OVA-20mg-us
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pep-TRP-2mg-us
CAS 57773-63-4
Triptorelin acetate is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH), carrying a D-amino acid substitution that extends receptor affinity and metabolic stability relative to native GnRH. Its receptor pharmacodynamics and super-agonist mechanism have been characterized in neuroendocrine research (Lahlou, 2005, Annales d'Urologie). For Research Use Only. Not for human consumption.
For laboratory research use only · Not for human or veterinary use.
Description
Triptorelin acetate is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH), distinguished from the native hormone by a single D-amino acid substitution at position 6. This substitution extends its resistance to enzymatic degradation and increases its binding affinity for the GnRH receptor relative to endogenous GnRH, giving it a longer biological half-life and a sustained, super-agonist receptor-occupancy profile. It has been studied in neuroendocrine and reproductive-endocrinology research as a tool for characterizing pituitary gonadotroph signaling and hormonal feedback loops.
Lahlou (2005, Annales d'Urologie) characterized the pharmacokinetics and pharmacodynamics of triptorelin, describing its super-agonist receptor mechanism relative to native GnRH and to GnRH-antagonist compounds. Keating (2010, Drugs) reviewed a sustained-release triptorelin embonate formulation, examining its pharmacokinetic profile, LH and FSH gonadotropin-suppression kinetics, and safety observations across a multicentre study cohort in reproductive-endocrinology research. Dal Prato et al. (2004, Human Reproduction) examined a randomized comparison of triptorelin depot dosing regimens, measuring gonadotropin (LH, FSH) and estradiol response profiles used in reproductive-endocrinology research to characterize pituitary-suppression kinetics under different dosing schedules.
For Research Use Only. Not for human consumption.
Specifications
Shipping & Storage
Shipping
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In-transit handling
Lyophilized vials are shelf-stable and ship at ambient temperature. Storage in our warehouse is cooled; shipment does not require refrigeration.
Long-term storage
Lyophilized vials are shelf-stable at ambient temperature; refrigeration (2–8°C) extends shelf life. Refer to the batch-specific Certificate of Analysis for material-specific storage guidance. Once reconstituted, follow the storage instructions on the batch COA. Not for human or animal consumption.
Returns
Because these are research-grade biologics, we cannot accept returns on opened vials. Damaged-in-transit shipments are replaced at no cost within 7 days of delivery.
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